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frameshift mutation

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English

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Noun

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frameshift mutation (countable and uncountable, plural frameshift mutations)

  1. (genetics) A genetic mutation that either inserts or deletes a number of nucleotides that is not divisible by three (i.e., a non-integer number of codons), altering the reading frame of the portion of the gene downstream of the mutation and causing it to code for a completely different protein sequence.