myristylate

English

Etymology

From myristyl +‎ -ate (verb-forming suffix).

Verb

myristylate (third-person singular simple present myristylates, present participle myristylating, simple past and past participle myristylated)

1. To undergo myristoylation.
   • 2000 January 14, Minoru Tateno et al., “Regulation of JNK by Src During Drosophila Development”, in Science‎^[1], volume 287, number 5451, →DOI, pages 324–327:

     Src42A myri has a point mutation in codon 2, which causes an amino acid substitution from Gly 2 to Asp. Gly 2 is conserved in all members of the Src family and must be myristylated for localization of Src to the cellular membrane in mammals (10 ).

   • 1997 December 19, Tony Pawson, John D. Scott, “Signaling Through Scaffold, Anchoring, and Adaptor Proteins”, in Science‎^[2], volume 278, number 5346, →DOI, pages 2075–2080:

     Similarly, FRS2, which is myristylated and has a potential PTB domain, is specifically phosphorylated by receptors for fibroblast growth factor (FGF) and nerve growth factor (NGF) (39 ).