cisplatin

See also: Cisplatin

English

Structure diagram of cisplatin

Etymology

From cis- +‎ -platin (“platinum derivative”).

Pronunciation

• IPA^(key): /sɪsˈplæt.ɪn/

Noun

cisplatin (countable and uncountable, plural cisplatins)

1. (pharmacology, uncountable) A platinum-containing antineoplastic drug cis-diamminedichloro-platinum(II) (Cl₂H₆N₂Pt) that is cytotoxic and is used especially in the treatment of testicular and ovarian tumors and advanced bladder cancer.

   Synonyms: cisplatinum, cis-diamminedichloroplatinum, (initialism) CDDP

   • 2012 September 19, Alphy Rose-James, Sreelekha TT, “Molecular Markers with Predictive and Prognostic Relevance in Lung Cancer”, in Lung cancer international‎^[1], volume 2012, →DOI:

     BRCA1 sensitizes cells to apoptosis induced by antimicrotubulin agents like taxanes and vinca alkaloids and also abrogates the effect of DNA-damaging agents like cisplatin and etoposide [ 41 ].

2. (dated, countable) A platin, that is, a platinum-based antineoplastic, of which the class cisplatin is the archetypal member.

Hypernyms

• platin

Derived terms

• lipoplatin

References

• “cisplatin”, in Lexico, Dictionary.com; Oxford University Press, 2019–2022.
• “cisplatin”, in Merriam-Webster Online Dictionary, Springfield, Mass.: Merriam-Webster, 1996–present.

Anagrams

• plasticin