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benzonase

From Wiktionary, the free dictionary

English

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Etymology

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From benzon (nucle)ase.

Noun

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benzonase (countable and uncountable, plural benzonases)

  1. (genetics) An artificial endonuclease used to degrade DNA and RNA.
    • 1991 October, J. M. Moreno, “Hydrolysis of nucleic acids in single-cell protein concentrates using immobilized benzonase”, in Applied Biochemistry and Biotechnology volume, volume 31:
      Hydrolysis of nucleic acids for single-cell protein concentrates has been carried out in one step using immobilized benzonase on corn cob.
    • 1999, Andrew J. Link, 2-d Proteome Analysis Protocols, page 83:
      The volume of benzonase solution (ready-made solution of the manufacturer) necessary to digest the DNA in the pellet III suspension was determined experimentally.
    • 2000 October, P. Ravindra, Anupama, Value-added food:: Single cell protein, in Biotechnology Advances, volume 18, issue 6, pages 459-479:
      Immobilized nucleases like benzonases on corncobs were also used to reduce the nucleic acid content in protein concentrates.
    • 2011, Charles Y. Lee, Korkut Uygun, Methods in Bioengineering: Organ Preservation and Reengineering, page 185:
      Treat the lung with benzonase to remove the remnant DNA:
    • 2014 May 23, Muniasamy Neerathilingam, “Soni-removal of nucleic acids from inclusion bodies”, in Biochemical and Biophysical Research Communications, volume 448, number 1, page 45:
      Also, in many cases, enzymes like benzonases fail to completely remove nucleic acids from complexes due to inaccessibility of shorter nucleic acids buried in the refolded protein as demonstrated in this study.
    • 2015, Antonio Monari, Elise Dumont, Chryssostomos Chatgilialoglu, Radiation-induced and oxidative DNA damages, page 42:
      The new digestion protocol was designed based on the enzymatic combination of benzonase and P1 nucleases.

Usage notes

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Capitalized when referring to a commercial product.