veratridine
English
[edit]
Noun
[edit]veratridine (uncountable)
- (organic chemistry) Any of a family of neurotoxic steroid-derived alkaloids, occurring in herbs of the genus Veratrum and seeds of the sabadilla plant.
- 1990, Dietrich Mebs, Ferdinand Mucho, “7: Toxins Acting on Ion Channels and Synapses”, in W. T. Shier, editor, Handbook of Toxinology, page 513:
- Like batrachotoxin and veratridine, grayanotoxins act at the voltage-dependent sodium channel in its open conformation, inhibiting its inactivation.
- 2013, Thomas D. White, The Demonstration and Measurement of Adenosine Triphosphate Release from Nerves, David Paton (editor), Methods in Pharmacology, Volume 6: Methods Used in Adenosine Research, page 47,
- The veratrum alkaloid, veratridine, depolarizes excitable tissues by activating the Na+ channels present in the cell membranes. Therefore, one would expect veratridine to produce a depolarization of nerve that is quite similar to physiological depolarization insofar as it is mediated by changes in Na+ conductances.
- 2013, Domingo M. Aviado, The Lung Circulation, Volume 1: Physiology and Pharmacology, page 39,
- The results from veratridine will be described first because they illustrate the ultimate way of obtaining proof that the carotid sinus baroreceptors can respond to foreign chemical agents.