tolbutamide

English

tolbutamide (countable and uncountable, plural tolbutamides)

A drug that blocks potassium channels, used in the treatment of diabetes.
- 2009 March 27, Ken-ichi Takeuchi et al., “Changes in Temperature Preferences and Energy Homeostasis in Dystroglycan Mutants”, in Science‎^[1], volume 323, number 5922, →DOI, pages 1740–1743:
  The cryophilic phenotype of the atu mutant was alleviated to some extent by administering rotenone, a pharmacological inhibitor of oxidative phosphorylation, but not tolbutamide, a sulphonylurea that stimulates metabolic rate by raising the lymphatic concentration of glucose.