oligometastasis

English

oligometastasis (countable and uncountable, plural oligometastases)

(medicine, pathology) A state of limited metastasis, especially of cancer, with several (but not many) metastatic sites.
- 2015, Hiroyuki Kaneda, Yukihito Saito, “Oligometastases: defined by prognosis and evaluated by cure”, in Cancer Treatment Communications, volume 3, →DOI, pages 1–6:
  Despite an increasing interest in oligometastases, the definition of the term “oligometastases” can be very confusing because it has been dependent on the particular research. Many researchers have defined oligometastases as metastases that are limited in both number (typically, less than 5) and location. Another confusing issue is outcome evaluation; researchers have evaluated the outcome of oligometastases by overall survival or local control. […] Hellman and Weichselbaum originally proposed the state of oligometastases in 1995 based on a consideration of the multistep nature of cancer progression. They proposed the existence of an oligometastatic state that was an “intermediate between purely localized lesions and those widely metastatic”. The state was expounded to be “amenable to a curative therapeutic strategy” and “amenable to localized therapy”.
(medicine, pathology) Any of the several metastatic tumors/sites in such a state.

The precise meanings of the term, including variations thereof, have been reviewed in the medical literature. ^[1]^[2]^[3]

^ Hellman S, Weichselbaum RR (1995) “Oligometastases”, in Journal of Clinical Oncology, volume 13, number 1, →DOI, →PMID, pages 8-10.
^ Tom Treasure (2012) “Oligometastatic cancer: an entity, a useful concept, or a therapeutic opportunity?”, in Journal of the Royal Society of Medicine, volume 105, number 6, →DOI, →PMID, →PMCID, pages 242-246.
^ Hiroyuki Kaneda, Yukihito Saito (2015) “Oligometastases: defined by prognosis and evaluated by cure”, in Cancer Treatment Communications, volume 3, →DOI, pages 1-6.