obinutuzumab

English

Etymology

From [Term?] +‎ -tu- (“tumor”) +‎ -zumab (“humanized monoclonal antibody”).

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Noun

obinutuzumab (uncountable)

1. (pharmacology) Synonym of afutuzumab.
   • 2015 July 23, “Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities”, in PLOS ONE‎^[1], →DOI:

     Recently, mogamulizumab (anti-CCR4 antibody, Kyowa Hakko Kirin) and obinutuzumab (anti-CD20 antibody, Genentech/Roche) with depleted core fucoses have been approved for marketing, and several glycoengineered antibodies are in clinical studies and are being developed as next generation therapeutic monoclonal antibodies.