nonsterol
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English
[edit]Etymology
[edit]Noun
[edit]nonsterol (plural nonsterols)
- Any organic compound that is not a sterol (but typically, having a somewhat similar structure)
- 2014 May 24, Lindsey L. Morris et al., “Sequential Actions of the AAA-ATPase Valosin-containing Protein (VCP)/p97 and the Proteasome 19 S Regulatory Particle in Sterol-accelerated, Endoplasmic Reticulum (ER)-associated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase*”, in The Journal of Biological Chemistry[1], volume 289, :
- Once ubiquitinated, reductase becomes dislocated from ER membranes into the cytosol for degradation by 26 S proteasomes through poorly defined reactions mediated by the AAA-ATPase valosin-containing protein (VCP)/p97 and augmented by the nonsterol isoprenoid geranylgeraniol.