mercapto protease

English

Etymology

From mercapto +‎ protease.

Noun

mercapto protease (plural mercapto proteases)

1. (biochemistry) A protease that contains an active sulfhydryl group.
   • 2005, "Proceedings on Rose Breeding, Cultivation and Production in China", Y Lin, Q Liu, IV International Symposium on Rose Research and Cultivation, actahort.org

     Mercapto-protease and serine protease were both found in rose petals.

   • 2017, December 8, Chenguang Biotech Group Co Ltd, "Lycopene micro-capsule powder and preparation method therefor", European Patent Office EP3721874A1

     The protease may be mercapto protease, preferably papain.

   • 2020, "Electrochemical detection of silver ions by using sulfur quantum dots modified gold electrode", L Fu, A Wang, K Xie, J Zhu, F Chen, H Wang, et al., Sensors and Actuators B: Chemical, Elsevier

     The principle is that silver ion can inhibit the activity of free mercapto protease and thus inhibit its biological function [[4], [5], [6]].

   • 2020, X LiuY ZhangS WangC LiuT WangZ Qiuet al., “Performance comparison of surface plasmon resonance biosensors based on ultrasmall noble metal nanoparticles templated using bovine serum albumin”, in Microchemical Journal, Elsevier:

     Considering that papain is a mercapto protease enzyme, and sulfydryl groups of papain are deemed to show a strong affinity for Au and Ag (as was the case for BSA).

   • 2021, "Cloning, expression and characterization of metalloproteinase HypZn from Aspergillus niger", P Song, W Xu, K Wang, Y Zhang, F Wang, X Zhou, et al., PLoS one, journals.plos.org

     The cysteine protease inhibitor E-64 had little effect on enzyme activity, indicating that the HypZn active site does not contain cysteine and that it is not a mercaptoprotease.