litholytic

English

Etymology

From litho- +‎ -lytic.

Adjective

litholytic (comparative more litholytic, superlative most litholytic)

1. Pertaining to the dissolution of stones, especially calculi such as gallstones, kidney stones, etc.
   • 2001, Prakash Paranjpe, Indian Medicinal Plants: Forgotten Healers:

     Varuna is one of the best litholytic herbs and has been used throughout the ages for the treatment of urolithiasis and crystalluria.

   • 2007, William C. Langley, Pancreatitis Research Advances, →ISBN, page 265:

     In the clinical practice, citric acid therapy has some problems, including its taste, large volume to drink, need for hospitalisation, and unpredictable litholytic effect.

   • 2012, G.N. Tytgat, Chr.J Mulder, Procedures in Hepatogastroenterology, →ISBN, page 477:

     Chance of recurrence The follow-up of patients who have become stone-free after combined ESWL/ adjuvant litholytic therapy is still relatively short.

   • 2012, H. Fleisch, Urolithiasis Research, →ISBN, page 553:

     Retrograde irrigation of the renal pelvis with litholytic solutions (Instrumental kidney stone chemolysis).

   • 2017, Tulasi Satyanarayana, Sunil K. Deshmukh, B.N. Johri, Developments in Fungal Biology and Applied Mycology, →ISBN, page 99:

     The secondary metabolites secreted by microbial flora of caves may cause chemical reactions with the substrate, contamination of the substrate. by pigments and lithogenic processes, litholytic processes, as well as cavern enlargement or speleotherm deposition.

Noun

litholytic (plural litholytics)

1. A medicinal substance that has a litholytic effect.
   • 1993, Joseph T. DiPiro, Pharmacotherapy: A Pathophysiologic Approach, page 618:

     Treatment options for symptomatic cholelithiasis include surgery, dissolution with oral bile salt litholytics or contact solvents, and current fragmentation.

   • 2007, William C. Langley, Pancreatitis Research Advances, →ISBN, page 265:

     Accordingly, citric acid, a calcium chelator, was selected as a pancreatic litholytic, and a 50-mg pancreatic stone was dissolved in vitro after 25 days ina solution of 3.9 mM/L citric acid, corresponding to a concentration of 749 μg/mL in the pancreatic juice following injection of citric acid into the canine duodenum.

   • 2016, Chughtai Bilal, Healing In Urology, →ISBN:

     Phyllanthus niuri (chanca piedra) herb is a traditional litholytic; its Spanish common name translates as “stone breaker.”