ibrutinib

English

Noun

ibrutinib (uncountable)

1. A targeted covalent inhibitor of Bruton's tyrosine kinase and hence used in treating B cell malignancies.
   • 2015 May 22, Georg Lenz, Martin Dreyling, “Insights into the Molecular Pathogenesis of Activated B-Cell-like Diffuse Large B-Cell Lymphoma and Its Therapeutic Implications”, in Cancers‎^[1], volume 7, →DOI:

     A recent high-throughput screen identified various compounds such as PI3K or BCL2 inhibitors that can be combined favorably with ibrutinib.

Synonyms

• PCI-32765
• (brandname) Imbruvica