hyperglutamatergic

English

hyperglutamatergic (not comparable)

(biochemistry, neurology) Excessively glutamatergic
- 2015 August 1, Dominique Endres et al., “Hypoglutamatergic state is associated with reduced cerebral glucose metabolism in anti-NMDA receptor encephalitis: a case report”, in BMC Psychiatry‎^[1], volume 15, →DOI:
  Therefore, we speculate that a model of a neuronal excitatory/inhibitory imbalance might explain the plethora of neuropsychiatric symptoms that can be observed in the course of NMDR encephalitis: Initial hyperglutamatergic states can be interpreted as an indicator of cortical over-excitation, whereas hypoglutamatergic states in the further course (after months) of the disease might be a sequel of over-inhibition of cortical brain areas, possibly triggered by the preceding over-excitation.