hypergalactosylated
English
[edit]Etymology
[edit]From hyper- + galactosylated.
Adjective
[edit]hypergalactosylated (not comparable)
- Excessively galactosylated
- 2015 December 12, “Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants”, in PLOS ONE[1], :
- We demonstrate a clear impact of glycosylation pattern on antibody stability and interaction with different FcγRs. Consistent with previous reports, deglycosylated antibodies failed to bind all Fcγ-receptors, with the exception of high affinity FcγRI. The FcγRII and FcγRIIIa binding activity of IgG1 was observed to depend on the galactosylation level, and hypergalactosylated antibodies demonstrated increased receptor interaction.