heteroduplices
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English
[edit]Noun
[edit]heteroduplices
- plural of heteroduplex
- 2002, S. Kleinle, K. Tabiti, S. Gallati, “Limitations of Melting Curve Analysis Using SYBR Green I – Fragment Differentiation and Mutation Detection in the CFTR-Gene”, in Wolfgang Dietmaier, Carl Wittwer, Natarajan Sivasubramanian, editors, Rapid Cycle Real-Time PCR – Methods and Applications: Genetics and Oncology, Springer-Verlag Berlin Heidelberg New York, →ISBN, part I (Methods Useful in Genetics and Oncology), page 55:
- Melting differences of heteroduplices compared to homoduplices are probably influenced by both the mutation and the surrounding sequence, e.g. for the 3905insT-mutation where one additional T is inserted into a stretch of 6 Ts.
- 2007, Cornel Mülhardt, Molecular Biology and Genomics (The Experimenter Series), Academic Press, →ISBN, pages 165–166:
- Because more homoduplices than heteroduplices develop after rehybridization, a rather intense background pattern is obtained from the digested homoduplices, which can cause the interesting bands to disappear.
- 2014, Mitchell Holland, Terry Melton, Charity Holland, “Forensic Mitochondrial DNA Analysis: Current Practice and Future Potential”, in Jaiprakash G. Shewale, Ray H. Liu, editors, Forensic DNA Analysis: Current Practices and Emerging Technologies, CRC Press, →ISBN, section IV (Expanding the Genotyping Capabilities), page 267:
- The DGGE technique allows for verification of heteroplasmy through the resolution of mismatch-containing heteroduplices from fully base-paired homoduplices in an increasingly denaturing environment.