dyotic
English
[edit]Etymology
[edit]Adjective
[edit]dyotic (not comparable)
- (physiology, of an endocrine signal) Causing differentiation between two states.
- 2011, Craig S. Atwood, Sivan Vadakkadath Meethal, Human Embryonic Stem Cells: A Model System for Delineating the Molecular Basis of Human Embryogenesis and Aging-related Diseases, page 261:
- In addition to the loss of neurons following the reactivation of the cell cycle in differentiated neurons, it is possible that dyotic signaling prevents normal neurogenesis from resident neural stem cells, thereby preventing replacement of neurons.
- 2011 July, Ian A. Clark, Craig S. Atwood, “Is TNF a link between aging-related reproductive endocrine dyscrasia and Alzheimer's disease?”, in Journal of Alzheimer's Disease, volume 27, number 4:
- It presents the evidence that dyotic endocrine signals modulate the expression of tumor necrosis factor (TNF) and related cytokines, and that these cytokines are a functionally important downstream link mediating neurodegeneration and dysfunction.
- 2013 February, James A. Yonker, Vicky Chang, Nicholas S. Roetker, Taissa S. Hauser, Robert M. Auser, Craig S. Atwood, “Hypothalamic–pituitary–gonadal axis homeostasis predicts longevity”, in Age, volume 35, number 1:
- Thus, the dysregulation of the hypothalamic–pituitary–gonadal (HPG) axis (endocrine dyscrasia) leads to altered (dyotic) signaling to somatic and reproductive tissues, driving re-entry of cells into the cell cycle.