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dihydroartemisinic acid

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English

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Noun

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dihydroartemisinic acid (uncountable)

  1. An acid that is a precursor to artemisinin.
    • 2015 July 9, Laura Bryant et al., “Proteomic analysis of Artemisia annua – towards elucidating the biosynthetic pathways of the antimalarial pro-drug artemisinin”, in BMC Plant Biology[1], volume 15, →DOI:
      What is known is that dihydroartemisinic acid can be converted non-enzymatically to artemisinin via an initial oxygenation to the corresponding tertiary allylic hydroperoxide, followed by Hock cleavage, and a second oxidative reaction on the resultant enolic intermediate.