bigenic

English

Etymology

From bi- +‎ genic.

Adjective

bigenic (not comparable)

1. Doubly transgenic
   • 2015 October 29, “Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin”, in PLOS ONE‎^[1], →DOI:

     Briefly, a Camk2α promoter was used to drive expression of the tetracycline transactivator protein (Camk2α-tTa), and a tetracycline responsive promoter was used to drive ΔNLS-hTDP-43 expression (tetO-ΔNLS-hTDP-43) such that ΔNLS-hTDP-43 protein expression was inhibited by doxycycline in bigenic mice (Camk2a-tTa x tetO-ΔNLS-hTDP-43).