afucosylate
English
[edit]Etymology
[edit]From a- + fucosylate.
Verb
[edit]afucosylate (third-person singular simple present afucosylates, present participle afucosylating, simple past and past participle afucosylated)
- (transitive, biochemistry, rare) To remove a fucosyl group from.
- Antonym: fucosylate
- 2015, Bauke Pauwels, Karin Jonstam, Claus Bachert, “Emerging biologics for the treatment of chronic rhinosinusitis”, in Expert Review of Clinical Immunology, volume 11, number 3, , →ISSN, page 355:
- By afucosylating benralizumab, it does not only binds[sic] IL-5Rα with a higher affinity, which leads to a competitive inhibition of IL-5, but also induces active apoptosis by antibody-dependent cell-mediated cytotoxicity [13,61,62].