LATE

See also: late

English

Noun

LATE (uncountable)

1. (pathology) Acronym of limbic-predominant age-related TDP-43 encephalopathy, a form of dementia.
   • 2019 June, Peter T Nelson et al., “Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report”, in Brain, volume 142, number 6, →DOI, page 1503:

     We describe a recently recognized disease entity, limbic-predominant age-related TDP-43 encephalopathy (LATE). LATE neuropathological change (LATE-NC) is defined by a stereotypical TDP-43 proteinopathy in older adults, with or without coexisting hippocampal sclerosis pathology.

   • 2020 March, Daniel Ferreira, Agneta Nordberg, Eric Westman, “Biological subtypes of Alzheimer disease: A systematic review and meta-analysis”, in Neurology, volume 94, number 10, →DOI:

     The clinical entity LATE (limbic-predominant age-related TDP-43 encephalopathy) has recently emerged.

   • 2020 May 14, Doreen Görß, Ingo Kilimann, Martin Dyrba, Sascha Nitsch, Bernd Krause, Stefan Teipel, “LATE: not every dementia is Alzheimer's disease”, in Der Nervenarzt, →DOI:

     The framework of LATE would account for the pathogenetic impact of limbic TDP-43 proteinopathy as a driver of amnestic dementia, either together with comorbid typical AD changes or as a distinct feature.

Anagrams

• teal, tael, et. al, atel-, TEAl, Elta, TEAL, et al, Teal, tale, tela, leat, EATL, ETLA, et al.