JAKinib

See also: jakinib

English

Alternative forms

• jakinib

Etymology

From JAK (“Janus kinase”) +‎ -in- +‎ -ib (“small molecule inhibitor”).

Noun

JAKinib (plural JAKinibs)

1. (pharmacology) A Janus kinase inhibitor.
   • 2019 July 8, Michael BonelliKarolina DalwigkAlexander PlatzerIsabel Olmos CalvoSilvia HayerBirgit Niederreiteret al., “IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes”, in Experimental & Molecular Medicine, volume 51, →DOI, page 1:

     Blocking the JAK-STAT pathway with the Janus kinase inhibitor (JAKinib) baricitinib or tofacitinib reduces the expression of IFN-regulated genes (IRGs) in TNF-activated FLSs. […] The IFN-signature might be a promising biomarker for the efficient and personalized use of new treatment strategies for RA, such as JAKinibs.