Hofmann rearrangement
Appearance
English
[edit]Etymology
[edit]Named after its discoverer, August Wilhelm von Hofmann.
Noun
[edit]Hofmann rearrangement (plural Hofmann rearrangements)
- (chemistry) The organic reaction of a primary amide to a primary amine with one carbon atom less. It involves oxidation of the nitrogen followed by rearrangement of the carbonyl and nitrogen to give an isocyanate intermediate.
- Synonym: Hofmann degradation