Jump to content

Hofmann rearrangement

From Wiktionary, the free dictionary

English

[edit]
English Wikipedia has an article on:
Wikipedia

Etymology

[edit]

Named after its discoverer, August Wilhelm von Hofmann.

Noun

[edit]

Hofmann rearrangement (plural Hofmann rearrangements)

  1. (chemistry) The organic reaction of a primary amide to a primary amine with one carbon atom less. It involves oxidation of the nitrogen followed by rearrangement of the carbonyl and nitrogen to give an isocyanate intermediate.
    Synonym: Hofmann degradation
[edit]