1732, George Smith, Institutiones Chirurgicæ: or, Principles of Surgery, [...] To which is Annexed, a Chirurgical Dispensatory, [...], London: Printed [by William Bowyer] for Henry Lintot, at the Cross-Keys against St. Dunstan's Church in Fleetstreet, →OCLC, page 254:
[…]Lanfrank takes Notice of Tract. 3. Doct. 3. cap. 18. ſaying, "I have ſeen many who being full of Humours, have made an Iſſue under the Knee, before due Purgation had been premis'd; whence, by reaſon of the too great Defluxion of Humours, the Legs tumified, ſo that the cauterized Place corrupted, and a Cancer (or rather cacoethic Ulcer) was thereby made, with which great Difficulty was cur'd."
1736, Daniel Turner, “Of Ulcers in General”, in The Art of Surgery: in which is Laid down such a General Idea of the same, as is Founded upon Reason, Confirm'd by Practice, and farther Illustrated with many Singular and Rare Cases Medico-chirurgical. In Two Volumes, 5th corr. edition, volume II, London: Printed for C[harles] Rivington in St. Paul's Church-Yard, and J. Clarke under the Royal Exchange, page 4:
[…] That all Ulcers which are ſtubborn or, as they are termed, rebellious, come under the Name of Cacoethic, a Word frequently met with in chyrurgic Treatiſes […]
1757, John Rutty, A Methodical Synopsis of Mineral Waters, Comprehending the Most Celebrated Medicinal Waters, both Cold and Hot, of Great-Britain, Ireland, France, Germany, and Italy, and several other Parts of the World, London: Printed for William Johnston, at the Golden Ball in St. Paul's Church-Yard, →OCLC, page 494:
On the ſurface of the water there floats a liquid bitumen, although it be every day ſcummed off, as it doth on the lake Aſphaltites in Judæa: The Inhabitants uſe it as pitch: it is alſo found to be an excellent vulnerary, and good in curing old cacoethic and ſcrophulous ulcers.
1833 August 24, Thomas Wakley, editor, The Lancet: MDXXXXXXII–XXXIII, volume II, number 521, London: Printed for the editor, by Mills, Jowett, and Mills, Bolt-Court, Fleet-Street, →OCLC, page 705:
At this time the attention of the class was arrested by a cacoethic case of Mr. WHITE, where the elasticity of the patient's constitution was very feeble, and one of the gentlemen remarked, that no formula in the Pharmacopœia or out of it would produce any effect on that disease.
1841, Paul Prendergast, “The Quack Doctor”, in Heads of the People; or, Portraits of the English, volume I, London: Robert Tyas, Paternoster Row, →OCLC, page 146:
According to the Anticacoethic theory, all diseases arise from the Cacoethes (a term derived from the Greek, to some of the philosophers of which country it is more than probable that the secret was known), and until the Cacoethic virus is expelled the system, vain are the efforts of the languishing sufferer to obtain a cure – an object which the Universal Anticacoethic Pills alone are the means calculated to effect.
1854, R[ussell] T[hacher] Trall, “Ulcers”, in The Hydropathic Encyclopedia: A System of Hydropathy and Hygiene. In Eight Parts: [...] Designed as a Guide to Families and Students, and a Text-book for Physicians, volume II, New York, N.Y.: Fowlers and Wells, →OCLC, page 356:
Ulcers are purulent solutions of the continuity of the animal texture. In a general sense, they are distinguished into the benign, or healthy, and the malignant, the indolent, and the irritable, etc. They are also subdivided into many varieties, according to their causes, nature, tendencies, consequences, etc., as simple, sinuous, fistulous, fungous, gangrenous, cancerous, scorbutic, syphilitic, scrofulous, inveterate, phagedenic, virulent, sordid, cacoëthic, carious, varicose, etc.
